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Print out your coupon, or bring it up on the Groupon app, and present it to the cashier. No credit card required. Sign Up or Sign In. Along with this complimentary guide, you will be entered into a holiday giveaway to win 25 books. Lose weight with Nutrisystem's top-rated plan, which includes delicious frozen foods. Save effortlessly with paperless coupons!

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Studies involving humans are for the most part badly designed. A few quality studies have been carried out over the years, starting in 1998 with a double-blind, placebo-controlled trial of 135 adults over 12 weeks published in The Journal of the American Medical Association. They found no evidence that hydroxycitric acid, the active ingredient in weight loss products made from garcinia cambogia, produced significant weight loss.

The American Journal of Clinical Nutrition in 2004 published a systematic review of meta-analyses and clinical trials on dietary supplements for weight loss by complementary medicine researchers at the Universities of Exeter and Plymouth.

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